Murphy, who took over from injured starter Jeff Driskel behind center Sept. 21, finished with three scoring passes in all, completing 16-of-22 throws for 240 yards.
Patton made six grabs overall for a career-high 124 yards as the Gators (4-1, 3-0 SEC) used a big second quarter to rack up a third straight win.
Loucheiz Purifoy helped out with a 42-yard interception return for a score.
The Razorbacks (3-3,0-2) were hampered by a sub-par game from Brandon Allen, who made good on only 17-of-41 passes for 164 yards.
Easer Egg Roll brings thousands to White House
Yosemite climber falls 30 feet, suffers major injuries