Jerry Rice wants the San Francisco 49ers to go after disgruntled Pittsburgh Steelers wide receiver Antonio Brown via trade.

The San Francisco 49ers gave up a lot of points and did not force many turnovers, but Robert Saleh will return for his third season as the 49ers' defensive coordinator, coach Kyle Shanahan said Monday.

The revolving door at quarterback in Tampa Bay took another spin this week and Jameis Winston will start when the Buccaneers host the San Francisco 49ers.

The New York Giants take on the San Francisco 49ers in Santa Clara in a battle of cellar dwellers on Monday night.

Nick Mullens told reporters Tuesday that San Francisco 49ers head coach Kyle Shanahan informed Mullens that he will start Monday's game.

Nick Mullens' superb Week 9 performance means a tough decision is ahead for Kyle Shanahan when it comes to naming the San Francisco 49ers' Week 10 quarterback.

The San Francisco 49ers could be down to their third-string quarterback on Thursday Night Football against the Oakland Raiders.

There's a lot at stake when the San Francisco 49ers host the Oakland Raiders on Thursday, but for all the wrong reasons.

San Francisco 49ers tight end George Kittle has made quite an impression on his teammates in his brief NFL career.

The Arizona Cardinals and San Francisco 49ers are suffering through eerily similar seasons.

The San Francisco 49ers are off to a disastrous 1-6 start but coach Kyle Shanahan told reporters Monday that he is not deviating from his plan to make the franchise relevant again in the NFL.

The Los Angeles Rams and San Francisco 49ers contest went as expected, with Los Angeles winning 39-10 at Levi's Stadium.

The San Francisco 49ers have been without their top three offensive skill players for the bulk of the season.

The Miami Dolphins aren't making any last-second quarterback changes ahead of Sunday's game against the Detroit Lions.

The unbeaten Los Angeles Rams are on the road again this week to face the 49ers on Sunday in Santa Clara.