Now on it's 10th installment, the celebrities gathered to read some of the worst things people have tweeted about them for Kimmel's most popular segment.
Most of the stars found the jabs funny, while others -- like Hugh Grant -- seemed confused at the segment's premise.
"Watching Hugh Grant and his stutteringly pathetic 'charm' is about as appealing to me as closing my scrotum on a DVD case," a bewildered Grant read to the camera.
"Are these real or do you make them up?" he asked producers.
Kate Hudson was able to find the humor in her tweet.
"Kate Hudson is a dead-eyed trash bag that smells like low tide," the actress read while laughing.
Captain America, Chris Evans, also laughed through his tweet, "Chris Evans is a stupid bearded sweater wearing dumb dork."
Greg Kinnear, Melissa McCarthy, Jane Lynch, Norman Reedus, Margot Robbie, Anthony Mackie, Judd Apatow, Olivia Wilde, Paul Rudd, Ryan Gosling, Zac Efron, Wanda Sykes, Russell Crowe, Bryan Cranston and Kiefer Sutherland all took part in the 10th edition.