Brian Williams went 5-of-6 from the field for 12 points and grabbed six rebounds for the Cowboys (12-1), who shot a sizzling 57.1 percent from the field to stay unbeaten at home.
Marcus Smart dished off eight assists to go with seven points. OSU totaled 27 assists overall, its most since 2000.
Karvel Anderson led the Colonials (5-9) with 16 points.
Swim Week Miami Beach 2014 [PHOTOS]