Jeremy Smith got most of his 18 points at the free-throw line, draining 14-of-15 foul shots, and Michael Dixon Jr. came off the bench to score 16 for Memphis (2-1), which had five players reaching double figures in scoring.
Nick King added 12 points and Chris Crawford supplied 11 for the Tigers.
Jeremy Smith paced Nicholls State (0-4) with 16 points.
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