Ben McLemore also grabbed seven rebounds while Jeff Withey provided 17 points, 10 boards and five blocks for the Jayhawks (20-4, 8-3 Big 12), who bested their intrastate rivals for the 38th time in 41 meetings.
The Wildcats (19-5, 8-3) got 20 points, six rebounds, four assists and four steals from Rodney McGruder but still saw their four-game winning streak snapped.
Angel Rodriguez donated 17 points, six assists and three 3-pointers in the loss.
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