Topic: Kyle Shanahan

The San Francisco 49ers are expected to activate Pro Bowl tight end George Kittle from injured reserve, clearing the way for him to play against the Arizona Cardinals on Saturday.

San Francisco 49ers wide receiver Deebo Samuel is expected to miss the remainder of the 2020 regular season because of a hamstring injury.

Coach Kyle Shanahan and San Francisco 49ers players were emotional after their Week 12 road win as they addressed the fact that they won't be able to return to their home stadium due to COVID-19 restrictions.

Fantasy football teams will be without two key running backs in Week 10, as Christian McCaffrey of the Carolina Panthers and Raheem Mostert of the San Francisco 49ers are both expected to miss their Sunday games.

Aaron Rodgers threw four touchdown passes and Davante Adams had 173 yards and a score on 10 catches to lead the Green Bay Packers to a lopsided "Thursday Night Football" victory over the San Francisco 49ers.

San Francisco 49ers quarterback Jimmy Garoppolo aggravated his high-ankle sprain and All-Pro tight end George Kittle sustained a new ankle injury during a Week 8 loss to the Seattle Seahawks.

The San Francisco 49ers rash of injuries continues as the NFL season enters Week 8, with wide receiver Deebo Samuel and running back Jeff Wilson Jr. each expected to miss an extended period of time.

Ahead of their matchup against the San Francisco 49ers on Sunday, New England Patriots head coach Bill Belichick said 49ers tight end George Kittle is "as good as anybody" he has coached against.

Miami Dolphins quarterback Ryan Fitzpatrick threw for 350 yards and three touchdowns while San Francisco's Jimmy Garoppolo struggled before he was benched in an upset loss on Sunday.

Carson Wentz rallied the Philadelphia Eagles for a second-half comeback over the San Francisco 49ers on Sunday Night Football to notch their first win of the season.