Jessica Chastain and Patti Smith will also each lend their voice to a chapter in the three-part space saga, which is scheduled to screen in its entirety for the first time at the Venice Film Festival, Variety said.
"It's fantastic to have Millie Bobby Brown narrate the second episode of Spheres -- not just because she's very talented but also because she has a huge following amongst millennials, which is our target demo with VR experiments like Spheres," producer Antoine Cayrol said.
Aronofsky posted on Instagram a mesmerizing clip from Brown's episode, which shows animated renderings of planets, which the 14-year-old, British actress can be heard slowly naming.
"We've always called to worlds beyond our own," she says in the brief preview.
"#firstlook of the final #vr episode of #spheres. @milliebobbybrown joins @jessicachastain and @thisispattismith in director @elizamcnitt incredible 3-part cosmo epic. world premier soon at the #venicefilmfestival www.experiencespheres.com," Aronofsky wrote.