Sarah Clarke (born February 16, 1972) is an American actress, best known for her role as Nina Myers on 24, and also known for her role as Renée Dwyer the 2008 film Twilight. She is also known for her leading role as Erin McGuire on the short-lived T.V show, Trust Me.

Clarke was born in St. Louis, Missouri, the daughter of Carolyn, a homemaker, and Ernest Clarke, an engineer.

Clarke attended Indiana University, where she studied Fine Arts and Italian. While a student at IU, Clarke became a member of the Kappa Alpha Theta sorority. She was initiated into the Beta chapter in 1990.