Patricia T. Arquette (born April 8, 1968) is an American actress and director. She played the lead character in the supernatural drama series Medium.
Arquette was born in Chicago, Illinois, the daughter of Lewis Arquette, an actor, and Brenda "Mardi" Olivia (née Nowak), an actress, poet, theater operator, activist, acting teacher and therapist. Arquette's mother was Jewish, the daughter of a Holocaust refugee from Poland, and Arquette's father was a convert to Islam and a descendant of explorer Meriwether Lewis. Her paternal grandfather was comedian Cliff Arquette, and her siblings are actors Rosanna, Alexis, Richmond and David Arquette.
Arquette was raised in Virginia and California.