The protests began at the end of January when a court sentenced 21 local residents to death for the murders of 72 people in the massive football stadium riot last year, MENA reported.
Following the verdict, 40 people died in clashes with security forces.
Protesters are demanding justice for the killing of both groups, MENA said.
Groups of protesters in Port Said have closed down two customs checkpoints, stopped railway movement and closed the seaport, MENA said.
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Syrian Al Qaida group executes Lebanese soldier