One of the men, who were captured in the Faizabad district of Badakhshan province, was injured during the operation and received medical treatment, the ISAF said in a release.
The injured man was responsible for suicide bombings against senior Afghan officials in Badakshan and Kunduz provinces, while the other man was a bomb-making expert who also helped plan the attacks, the release said.
The operation also netted an additional suspected insurgent and a suicide vest, explosives, blasting caps and detonation cord.
A separate coalition operation in the south of the country captured a Taliban leader in Helmand province. Other Taliban facilitators were captured in additional operations.
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