"Unfortunately, due to the logistics involved and timing complications, Amy will not be coming to the U.S. this weekend to perform at the Grammys in Los Angeles," Winehouse's representative said in a statement issued to TMZ.com Friday. "However, she will still be performing via satellite broadcast from London, as previously announced this morning."
The spokeswoman added Winehouse is "very sad" not to be able to attend.
Winehouse, who is nominated for six Grammys, has been in rehab since last month.
Six-time Grammy winner Tina Turner also is slated to join two-time nominee Beyonce for a special performance.
Akon, Jason Bateman, Dierks Bentley, Tony Bennett, Cher, Nelly Furtado, Cuba Gooding Jr., Tom Hanks, Quincy Jones, Carole King, Joe Mantegna, Prince, Roselyn Sanchez, Ringo Starr, Dave Stewart, will.i.am and Stevie Wonder have been added to the list of presenters.