The run came midway through the second quarter of the Titans' 30-9 AFC South thrashing on Thursday at Nissan Stadium in Nashville, Tenn. Henry finished the game with 238 yards and four touchdowns on 17 carries.
"Trying to catch my breath," Henry told reporters. "No, I'm just kidding. It's so crazy, because before when we were in the huddle, they were like, 'You got to break a 99-yard.'"
"My main focus is to get positive yards, but when I had the ball and I got it, I just saw it and I just hit it. My stiff arm was working, so that's all about that. But, like I said, it started upfront with those guys. All of us, 11 of us, executing that play for that to happen."
Titans quarterback Marcus Mariota handed the ball off to his left, putting it in Henry's chest in the end zone on the play. Henry crossed the goal line, blasting through the Jaguars defensive line before turning on the jets. He came up on Jaguars cornerback A.J. Bouye at the 20-yard line and deployed a serious stiff-arm, sending the defender to the ground.
Henry flew down the left flank before sending away linebacker Leon Jacobs with another stiff-arm. Henry gave Myles Jack another stiff arm before finally reaching the end zone.
"Well, I think when you're going to look at the film, I don't think you're going to see the effort," Jaguars coach Doug Marrone said. "You're going to say why you got stiff armed on the tackle. We just didn't get him down. There were guys around him. You see a hit, he goes on, another guy is running, guys running from the other side of the field, guys running from behind."
"We just didn't tackle him. When you look at the film, that's what you're going to see. At the end of the game, the effort, I mean, we stop him. We give them the ball back in our territory, we go for a fourth down, we don't get it, and those guys come in there and they get a stop."
The run gave the Titans a 14-7 lead. Henry scored all of the Titans' touchdowns in the victory. The Titans running back now has 712 yards and nine touchdowns on 145 carries this season. His run on Thursday was the longest of the 2018 season.