Derrick Henry used a powerful stiff-arm and serious speed to break free for a 99-yard touchdown during the Tennessee Titans' win against the Jacksonville Jaguars.

Derrick Henry had a video-game-type night Thursday night, rushing for a franchise-record 238 yards and four touchdowns.

If the Buffalo Bills needed him to play two weeks ago in New York, rookie quarterback Josh Allen would have given it a try.

For six consecutive seasons starting in 2011, the Jacksonville Jaguars were the laughing stock of the NFL.

As Week 10 hits in the NFL, several teams have issues keeping their offenses stable and healthy.

Running back Leonard Fournette is expected to play for the Jacksonville Jaguars on Sunday against the Indianapolis Colts after missing the last four games.

At the highest point of their quarterback careers, the Indianapolis Colts' Andrew Luck and Jacksonville Jaguars' Blake Bortles advanced their respective teams to AFC Championship Game losses at New England.

Will an extended time span away from the locker room and practice field result in a change of fortune for the Jacksonville Jaguars?

Head coach Doug Marrone and the Jacksonville Jaguars are running out of options.

Coming off a Thursday night game in which the Houston Texans lost Will Fuller for the season with a torn ACL, several other teams declared their receivers out.

Jacksonville Jaguars cornerback A.J. Bouye will not travel to London with the team for their game against the Philadelphia Eagles because of a calf injury.

Injuries happen in professional football. It's a part of the game that everyone accepts as just being another element in what makes the sport so appealing.

The Jacksonville Jaguars believed they made a statement by avenging their AFC Championship Game defeat in Week 2, only to fall flat in their next contest.

The Jacksonville Jaguars let the New England Patriots off the ropes in the AFC Championship, only to find themselves down for the count.

The Jacksonville Jaguars have signed free agent cornerback Charlie Miller.