"I'm such a positive person, I tested positive AGAIN. I am feeling fine - the great John @Mulaney & Andy Samberg @TheLonelyIsland have graciously agreed to host @JimmyKimmelLive for me tomorrow," the comedian tweeted.
Kimmel only recently returned to hosting his late night talk show after testing positive earlier in May. Comedian Mike Birbiglia stepped in as guest host at the time.
Stephen Colbert of The Late Show had also tested positive for COVID-19 in April, but has recently returned to resume his hosting duties.