The clip, released Thursday, features the pop star in major cities such as Miami, Tokyo and London as she parties and meets up with her two collaborators.
After Swift walks the beaches of Miami and rides in a Lamborghini with Future, she is seen hanging out with Sheeran in Tokyo where she borrows the singer's glasses and begins dancing comedically.
Other moments from the video include Swift riding on a motorcycle, giving cheers at a bar and enjoying a party on a boat.
The "End Game" music video is the third directed by Joseph Kahn who also helmed the videos for "Look What You Made Me Do" and "...Ready for It?" All three songs appear on Swift's latest album, Reputation.