Kudrow previously starred in the TV shows "Friends" and "The Comeback."
The new geneology series called "Who Do You Think You Are?" will be made in conjunction with Kudrow's production company Is or Isn't Entertainment, as well as Britain's Wall to Wall Productions.
The show is based on the BBC television documentary series created and executive produced by Alex Graham.
The announcement regarding the show was made Tuesday by NBC Entertainment's Craig Plestis.
"This engaging new series gives viewers a glimpse into the personal lives of our favorite celebrities allowing us to learn not only more about that individual, but also about our country's history on a grand scale," Plestis said in a statement.
"The show's combination of wonderful storytelling and powerful emotion has made it a break-out hit with British viewers and we're sure American audiences will love it too," added Graham, the show's creator and executive producer. "We're thrilled that a star of the caliber of Lisa Kudrow has such faith in the show that she wanted to be a part of the creative team."