Indianapolis Colts quarterback Andrew Luck, in a surprise announcement, said he made the "hardest decision of my life" to retire from the NFL at age 29, citing frequent injuries.

Indianapolis Colts starting quarterback Andrew Luck is expected to miss the entire preseason due to a high-ankle injury.

Indianapolis Colts head coach Frank Reich admitted he is "excited" about the positive attention from fans and analysts.

Dallas Cowboys running back Ezekiel Elliott leads UPI senior sports writer Alex Butler's top 200 player rankings for the 2019 fantasy football season.

Zach Ertz and Travis Kelce top UPI senior sports writer Alex Butler's 2019 season fantasy football tight end rankings.

Andrew Luck, Patrick Mahomes and Baker Mayfield top UPI senior sports writer Alex Butler's 2019 season fantasy football quarterback rankings.

Indianapolis Colts coach Frank Reich and Tennessee Titans coach Mike Vrabel told UPI that several factors make quarterbacks like Andrew Luck elite, including a specific level of poise.

Indianapolis Colts rookie center Javon Patterson will miss the 2019 season after tearing his ACL Tuesday in practice.

The Professional Football Writers of America named Pittsburgh Steelers linebacker Ryan Shazier the recipient of the 2019 George Halas Award.

Colts quarterback Andrew Luck and actor Tom Hanks talked about the pressures of the NFL during an event for military families in Indianapolis.

Indianapolis Colts quarterback Andrew Luck will not participate in OTAs this week after sustaining a calf strain.

The Indianapolis Colts have signed free agent quarterback Chad Kelly, the nephew of Hall of Fame quarterback Jim Kelly.

Indianapolis Colts tight end Eric Ebron is coming off of a breakout season, but has his eyes on a Rob Gronkowski record in 2019.

Marcus Mariota's Tennessee Titans teammates told UPI that they support their quarterback as a leader and are excited to see how he performs in 2019.

The 2019 NFL season schedule is out and UPI has you covered with the best games to watch and point spreads for the Week 1 slate.