BALTIMORE, June 26 (UPI) -- Derrek Lee and Mark Reynolds each smashed fourth-inning homers Sunday, handing the Baltimore Orioles a 7-5 interleague victory over Cincinnati.
Adam Jones and Vladimir Guerrero led off the fourth with singles and Lee then belted the first pitch from Homer Bailey (3-2) deep into the left field seats for a three-run homer and a 4-0 Orioles lead.
One batter later, Reynolds connected for a solo shot and the Orioles went on to take the rubber match of a three-game set against the Reds.
Luke Scott also homered and Nick Markakis went 3-for-5 with two RBI in the O's win.
Jeremy Guthrie (3-9) logged his first victory since May 21, allowing four runs on six hits over 5 2/3 innings, walking four and striking out five.
Kevin Gregg picked up his 14th save despite allowing a run in the ninth.
Brandon Phillips and Ramon Hernandez each socked solo homers for Cincinnati.