Manilow sang and played the piano, while a screen showed video footage of Houston looking glamorous and performing her part of the ballad, which appears on Manilow's new album My Dream Duets.
"They asked me to do a duets album and I thought, 'How can I make my duets album different than everybody's?' And I picked all these people that I would have loved to sing with, but they are all gone," Manilow explained before performing on the talk show. "So, I did duets on this album with John Denver, Judy Garland, Whitney Houston, Louis Armstrong. It's a long list of famous, famous singers and they figured out a way of helping me to make a beautiful album of these famous people singing their songs. Andy Williams doing 'Moon River' with me! Really, it's a beautiful album."
"Now, did they just pull the vocals and you sang with the original vocals?" View co-host Rosie O'Donnell wanted to know.
"Yeah, we got rid of all the orchestra. I re-orchestrated, re-arranged it with a brand new band and I made duets out of the vocals. It was really emotional hearing Whitney just by herself. I had to push myself away from the speakers. She was standing right next to me. Really, I would sing with her and then I would go for the Kleenex," Manilow revealed.
As he wrapped up the song, Manilow told the video screen, "Sing to us, Whitney!"
Houston accidentally drowned while she was intoxicated in a hotel bathtub in 2012. She was 48.