But Profar's blast off J.C. Gutierrez (0-1) in the next half-inning put Texas back on top.
David Murphy later added an RBI single for an insurance run as the American League West-leading Rangers took the rubber match of a three-game series.
Tanner Scheppers (4-0) earned the victory after starter Yu Darvish had blanked the Royals on three hits over seven innings.
Kansas City's Ervin Santana also pitched well in a no-decision, yielding just one unearned run on three hits in seven frames.
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