"I look good, I'm still so tired from Sunday, I tried really hard. We won!" the comedian responded after being asked about the big game, appearing unaware of how football works.
"I'm thinking I'm so far from the line and I have to get it to the, I gotta do it, gotta get this ball to the guy," she continued, hilariously describing the final moments of Super Bowl 50.
Fallon then proceeded to ask the Ghostbusters star a series of rapid-fire questions about some of Manning's favorite things in which Wiig revealed that the athlete's favorite pregame meal consisted of "french fries and toast" with his favorite band being "Maroon 5."
Wiig's impersonation ended after Fallon challenged the actress to display her athletic ability by throwing a golden football through a small hole. Wiig's missed the mark considerably, much to the audience's delight.
Wiig can next be seen in the fashion comedy sequel Zoolander 2 now in theaters.