Study indicates COVID-19 antibodies may fade after months

Mannequins with face masks and designer clothing fill a window at a Diane Von Furstenberg store in New York City on September 8, 2020. Photo by John Angelillo/UPI | License Photo

July 13 (UPI) -- A study has found that COVID-19 antibodies may diminish rapidly within three months of peaking, meaning that any new vaccine against the disease might possibly offer only temporary protection.

The research by King's College London has not yet been peer-reviewed, but adds to a growing body of evidence suggesting that the human body cannot produce long-term antibodies against SARS-CoV-2, the novel coronavirus responsible for COVID-19.


The results of the study -- which involved more than 90 patients and healthcare workers at British hospitals -- showed that just 17 percent of those who produced a strong antibody response to the virus were able to maintain that potency after three months.

Antibody levels fell by as much as 23 times and disappeared altogether in some cases, researchers said.

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"People are producing a reasonable antibody response to the virus, but it's waning over a short period of time and depending on how high your peak is, that determines how long the antibodies are staying around," lead author Dr. Katie Doores told The Guardian.

"People may need boosting and one shot might not be sufficient."

Earlier studies conducted in China and Spain also suggested that immunity to COVID-19 may decline over time.


The results also cast some doubt on the effectiveness of "herd immunity" strategies, which rely on the assumption that populations cannot become reinfected once exposed to the virus.

The British government initially considered avoiding strict lockdowns in the hopes of gaining herd immunity, but quickly abandoned those plans when health officials predicted the country's hospitals would be overwhelmed.

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Visitors wear face masks as they tour the Whitney Museum of American Art as it reopens on September 3. Photo by John Angelillo/UPI | License Photo

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