Levy missed 11 games this year with various injuries before returning for the final four games of the season. He was limited in practice this week with a knee injury.
Center Travis Swanson (concussion), offensive tackle Riley Reiff (hip) and returner/wide receiver Andre Roberts (shoulder) also were listed as questionable for the Lions (9-7). They were limited participants in Friday's practice.
For the Seahawks (10-5-1), running back C.J. Prosise (shoulder) and defensive tackle Tony McDaniel (concussion) were officially ruled out.
Cornerback Richard Sherman, defensive end Michael Bennett and tight end Jimmy Graham were listed on the injury report, but the team said it was not injury related. All three were full participants in practice all week.