The Yankees slugger got it going early Tuesday at Yankee Stadium in New York City. Stanton hit his first bomb in the bottom of the second inning out of the cleanup spot.
He stepped in to face Drew Pomeranz for the exchange. The southpaw tossed in a called strike, before working the count to 1-2 against Stanton. Stanton rebounded to push the count full, before hacking away at Pomeranz's seventh offering.
The Yankees' biggest offseason splash sent the 91.7-mph fastball for a 372-foot solo shot to left field, giving his squad a 1-0 edge.
New York held on to that lead until Stanton was back up at the plate in the bottom of the fourth frame. He settled in against Pomeranz once again, but this exchange was a bit more brief.
Stanton worked a 2-1 count against the Red Sox starter, before mashing an 88.9-mph fastball to right field for a 375-foot solo shot.
Yankees star Aaron Judge knocked in the go-ahead run with an RBI single in the bottom of the seventh frame.
"As long as it's helping us win the game, it doesn't matter the opponent," Stanton told reporters. "It's always a little sweeter with the rivalry."
Stanton went 2-for-3 at the plate, with two runs scored, two RBIs and a walk. He is now hitting .237 on the season, with nine home runs and 21 RBIs. The 2017 National League MVP leads baseball with 53 strikeouts.
Giancarlo Stanton's 3rd multi-homer game of the season propels New York past their Boston rivals. pic.twitter.com/ghrcihltDq— YES Network (@YESNetwork) May 9, 2018
The Yankees and Red Sox are now tied atop the American League East and share the best record in the majors.