NFL: San Diego 23, Indianapolis 21

SAN DIEGO, Nov. 12 (UPI) -- Darren Sproles ran a punt and a kickoff back for touchdowns Sunday night, and the San Diego Chargers held on to beat Indianapolis, 23-21.

LaDainian Tomlinson finished with 21 carries for 76 yards and one touchdown while Antonio Cromartie had three interceptions for the Chargers, who have won four of their last five games.

Philip Rivers completed just 13-of-24 for 104 yards and two interceptions for San Diego.

Peyton Manning threw a career high six interceptions on 34-for-56 passing with 328 yards and two touchdowns.

Reggie Wayne caught 10 passes for 140 yards and a touchdown for the Colts, who have lost two in a row.