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Veterinarians said Sais took the canine away from the facility after they confirmed Jack tested positive for the drug.
"Doctors observed Jack suffering from convulsions and seizures and felt Jack's life was in jeopardy," police said in a news release.
The clinic contacted the Fontana Animal Services Team, which sent officers to Sais' home.
The officers found Jack Sparrow "still suffering from the effects of the drug and other signs of general neglect," police said.
The canine was seized and returned to the veterinary clinic, where he was treated and kept under observation.
A video posted to Facebook by the police department shows the chihuahua acting "twitchy" and "agitated."
Jack is expected to fully recover, police said.
Sais was arrested Friday afternoon on a charge of felony animal cruelty. He was booked into the West Valley Detention Center in Rancho Cucamonga.