The clip, released Wednesday, features Get Out star Lil Rel Howery asking Uncle Drew for help in winning a basketball tournament after losing his life savings. Uncle Drew agrees to enter if he can recruit his old team, which consists of other NBA stars portraying senior citizens including Shaquille O'Neal, Chris Webber, Reggie Miller, Nate Robinson and Lisa Leslie of WNBA fame.
ESPN teased the star-studded cast in September.
"You don't stop playing because you're getting old, You're old because you stop playing," Irving says in the trailer that also features comedians Tiffany Haddish and Nick Kroll.
Uncle Drew, directed by Charles Stone III and produced by Wyck Godfrey and Marty Bowen, is based on a fan-favorite digital episodic series created by Pepsi that starred Irving as the title character.
Uncle Drew is set to arrive in theaters on June 29.