"I'd consider anything with the right director," the actor said to the Irish Examiner while attending the U.K. premiere of Jason Bourne after he was asked about the internet's suggestion of playing Robin to Affleck's Batman.
"But I can't imagine there are any superheroes left, I think they're all taken at this moment," he continued before noting how his Hollywood best friend could get him to become a superhero regardless.
"If he (Ben) was directing me, I'd jump on it in a New York minute. I'd love to work with Ben. The problem with Ben is every time he directs a movie, he gives himself the best role in it, so until he's willing to give up the best role to one of his friends, we're not going to get on with it."
Damon will next be seen in the action sequel Jason Bourne due in theaters July 29. During a promotional tour for the film in South Korea, the 45-year-old mentioned to The Hollywood Reporter how he is "totally fine" with a younger actor taking over the role once he is done with the franchise.
"Definitely going to be replaced some day by some new young Jason Bourne. That happens to everybody and they reboot these things, and that's totally fine," he said.
"The only control I can exercise is over the ones that I'm part of. I'm the curator of them as long as I'm involved and that's why I battled so hard to make sure that we got the same creative people [including director Paul Greengrass] to get involved in this one," he continued.