Christine Jorgensen (May 30, 1926 – May 3, 1989) was the first widely-known individual to have sex reassignment surgery—in this case, male to female.

Jorgensen was born George William Jorgensen, Jr., the second child of George William Jorgensen Sr., a carpenter and contractor, and his wife, the former Florence Davis Hansen. Jorgensen grew up in the Bronx and later described herself as having been a "frail, tow-headed, introverted little boy who ran from fistfights and rough-and-tumble games".

Jorgensen graduated from Christopher Columbus High School in 1945 and shortly thereafter was drafted into the Army.