Robert Charles Joseph Edward Sabatini Guccione (b. December 17, 1930 in Brooklyn, New York) is the founder of the adult magazine Penthouse and was, until his resignation in November 2003, its publisher.

Guccione was born in Brooklyn, New York, and raised in Bergenfield, New Jersey. He attended high school at Blair Academy, a prep school in Blairstown, New Jersey. In his youth, he traveled widely, and had wild adventures with friends like William S. Burroughs in Tangier. He sometimes earned his living as an artist, creating cartoons in the 1950s for Bill Box's humorous greeting card company, Box Cards.

At the height of his success, Guccione was considered to be one of the richest men in the United States. He was once listed in the Forbes 400 ranking of wealthiest people ($400 million net worth in 1982). An April 2002 New York Times article quoted Guccione as saying that Penthouse grossed $3.5 billion to $4 billion over the 30-year life of the company, with a net income of almost half a billion dollars.