"She's eager to get back to the office," Deputy Assistant Secretary of State Philippe Reines said in a statement, NPR reported. "Her medical team advised her that she is making good progress on all fronts, and they are confident she will make a full recovery."
Clinton, 65, who checked in to NewYork-Presbyterian Hospital Sunday with a blood clot -- apparently caused when she fell and suffered a concussion -- had been seen earlier Wednesday walking to a waiting van outside the hospital, driven by her security detail, the New York Post reported.
Clinton was treated with blood thinners during her hospital stay and was expected to make a full recovery, doctors have said.
State Department spokeswoman Victoria Nuland said Clinton had been working from her hospital bed, even though she hasn't been seen in public since Dec. 7.
"She's been quite active on the phone with staff and taking paper, etc.," Nuland said.
Clinton fell at her Washington home last month after suffering dehydration because of a stomach virus. The illness forced her to cancel some foreign travel and testimony before Congress.