New Jersey won for the second time in eight games this season while snapping the Raptors' two-game winning streak.
The Nets led by as many as 22 points in the fourth quarter, pulling away after being in front by just three early in the third.
Toronto got 19 points from Jose Calderon and 17 from Andrea Bargnani. New Jersey made 15-of-31 3-pointers.
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