Rodgers completed four TD passes and also ran in a pair of scores. He went 29-of-38 through the air, with seven passes going to Greg Jennings for 103 yards and a TD for the Packers (4-0).
Jordy Nelson made five grabs for 91 yards and a touchdown and James Starks picked up 63 yards on 13 carries in the victory.
Denver (1-3) was victimized by three interceptions tossed by Kyle Orton, who went 22-of-32 for 273 yards with three touchdowns.
His favorite target was Brandon Lloyd, who led all receivers with 136 yards on eight catches.
Eric Decker scored twice in the Broncos' loss.
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