The disease -- called Lymphogranuloma venereum -- is caused by a strain of Chlamydia and infects lymph glands in the genital area, the New York Post reported. The report said the disease has been detected in at least two people in the city.
The disease, which can be treated with antibiotics, had previously been detected in gay enclaves in San Francisco and Europe.
In some cases it can be transmitted through nonsexual contact, the report said.
Health Commissioner Thomas Frieden is expected to discuss prevention methods and treatment with several public-health advocacy groups.