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"We are devastated," Martin said. "We were in a race against time to get the weight off Meow before he developed complications from his obesity, and we lost."
"His extreme obesity may have set off a string of events that ultimately ended his life," said Jennifer Steketee, a veterinarian who accompanied Meow on his star-making April 23 appearance on "Today."
Martin said she hopes Meow's story will raise awareness of animal obesity.
"We hope his fight will encourage other people to help their pets maintain the best health possible," she said. "Obesity is not something to be ignored."