Police spokeswoman Eren Stephens said the bus, which is often seen operating downtown during Detroit Lions games, is being investigated on allegations of being an illegal strip club, charging $10 "donations" for entry, the Detroit Free Press reported Wednesday.
"We're looking at the whole operation, not just that they're going to every game," Stephens said.
Godbee said he ordered the investigation after a city official complained about the bus being parked downtown during Lions games, The Detroit News reported.
"Ostensibly, it's an illegal establishment," Godbee said. "The same thing that would regulate that type of activity in a strip club would be applicable to that vehicle. We're going to police it very aggressively through our investigation.
"I'm appalled at this kind of conduct because we have families and children around. We need to make sure these events are fan-friendly for children and their families," he said.
The department is also investigating photos on Facebook depicting two police officers posing with the bus, investigators said.
The Free Press and the News said the operators of the Booty Lounge could not be reached for comment.