Producers cut the chat short after Jameson, 39, seemed out of it while the cameras were rolling, the celebrity news website said.
Jameson was booked on the program to talk about her first novel, "Sugar."
This is not the first time she has been accused of substance abuse, TMZ said. She pleaded guilty to driving under the influence last year after she crashed her car into a light pole while on unspecified prescription drugs and her ex-boyfriend, Tito Ortiz, has claimed she is addicted to OxyContin.
The one-time adult-film actress has denied allegations she is addicted to the prescription painkiller.