The casting news was first reported by Deadline Hollywood.
Lucci starred on "All My Children" from its premiere in 1970 to its demise last summer.
The New York Post said the show is based on the Mexican telenovela format. It will follow four Beverly Hills maids and their wealthy employers, with one boss played by Lucci.
Actresses Ana Ortiz and Dania Ramirez also have joined the cast of the show, which is due to premiere in the fall, the Post said.
"Desperate Housewives" is wrapping up its eighth and final season this spring.