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The combination of the drugs phentermine and topiramate (trade name Qnexa) is an investigational medication for the treatment of obesity and related conditions such as type 2 diabetes and has been found to lower blood pressure and cholesterol.[1] Qnexa is being developed by Vivus, a California pharmaceutical company.[2] Phentermine is an appetite suppressant and stimulant of the amphetamine and phenethylamine class. Topiramate is an anticonvulsant that has weight loss side effects.