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Preston Knowles (born March 29, 1989) is a Senior guard for the 2010-11 University of Louisville men's basketball team. Knowles has been a defensive leader for the Cardinals and finished the 2009 season as the Big East leader in three-point shooting percentage.
He attended George Rogers Clark High School in Winchester, Kentucky. As a senior, he averaged 21.4 points, 7.1 rebounds, 2.6 assists and 2.2 steals.