Mark Patrick Sweeney (born October 26, 1969 in Framingham, Massachusetts) is a former first baseman in Major League Baseball. He is best known for his skill as a pinch hitter, where he is second on the all-time list for pinch hits.
Sweeney attended Holliston High School in Holliston, Massachusetts and was a student and a letterman in football and baseball. In baseball, he helped lead his team to the 1987 Massachusetts State Championship.
Sweeney was signed to play quarterback for the University of Maine in Orono. There he decided to play baseball full-time. He went on to become a Golden Spikes Finalist, playing outfield, and breaking many of the school's offensive records. As a senior he hit .384 with 23 home runs, 80 RBI and 22 stolen bases in 65 games.