San Francisco 49ers running back Jerick McKinnon's status for the regular season is uncertain after suffering a setback in his recovery from a torn ACL.

San Francisco 49ers running back Jerick McKinnon returned to the practice field after being removed from the physically unable to perform list.

Carolina Panthers running back Christian McCaffrey leads UPI senior sports writer Alex Butler's top 200 player rankings for the 2019 fantasy football season.

Christian McCaffrey and Saquon Barkley top UPI senior sports writer Alex Butler's 2019 season fantasy football running back rankings.

Running back Jerick McKinnon will remain on the San Francisco 49ers roster for the 2019 season.

The San Francisco 49ers gave up a lot of points and did not force many turnovers, but Robert Saleh will return for his third season as the 49ers' defensive coordinator, coach Kyle Shanahan said Monday.

The Denver Broncos are trying to keep pace in the AFC playoff race while scrambling to find replacements for two injured players ahead of their game Sunday against the host San Francisco 49ers.

An outstanding night by the San Francisco 49ers was tarnished by an ugly injury to Raheem Mostert.

The Arizona Cardinals and San Francisco 49ers are suffering through eerily similar seasons.

The San Francisco 49ers are off to a disastrous 1-6 start but coach Kyle Shanahan told reporters Monday that he is not deviating from his plan to make the franchise relevant again in the NFL.

The San Francisco 49ers have been without their top three offensive skill players for the bulk of the season.

It has been three years since the San Francisco 49ers and Green Bay Packers have squared off, but the teams will hook up Monday night at Lambeau Field.

The San Francisco 49ers could be without key players on both sides of the ball for Sunday's game against the visiting Arizona Cardinals.

The San Francisco 49ers traded for Jimmy Garoppolo midway in the 2017 season in what they hoped would be the first building block to turn around the franchise.

Franchise quarterback Jimmy Garoppolo is feared to have suffered a torn ACL in the San Francisco 49ers' loss to the Kansas City Chiefs at Arrowhead Stadium.