Donna Pescow (born March 24, 1954) is an American film and television actress and director.

Pescow was born in Brooklyn, New York, to a Jewish family. Her father owned and ran a news stand in downtown NYC at Battery Place. Pescow attended Sheepshead Bay High School in Brooklyn and she took drama classes with Rocky co-star Carl Weathers. Pescow studied at the American Academy of the Arts. Approximately 1973 or '74, Donna had a leading role in an off-off Broadway musical entitled Poor Old Fool. It was a short run of just a few weeks.

In 1977, Pescow had a successful role in the John Travolta film Saturday Night Fever. For this role, she had to relearn her Brooklyn accent and gain about 40 pounds. While both the role, and the film were huge successes, Donna later went on to appear in television roles for the majority of her career.

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