Moderna: Redesigned COVID-19 booster protects better against variants

Moderna is testing new versions of its COVID-19 vaccine aimed at new variants. File Photo by Keizo Mori/UPI | <a href="/News_Photos/lp/b91047d60441b1e37eac5cb6cf3b2106/" target="_blank">License Photo</a>
Moderna is testing new versions of its COVID-19 vaccine aimed at new variants. File Photo by Keizo Mori/UPI | License Photo

April 19 (UPI) -- Moderna announced Tuesday its redesigned COVID-19 booster ignites a stronger immune response against the Beta, Delta and Omicron variants than the shots currently on the market.

The biotech company has spent the last year developing the new vaccine to target various COVID-19 variants and produce longer-lasting protection.


Moderna tested the new vaccine on 895 participants in a clinical trial. Some participants received a 50-microgram dose and others received 100 micrograms. After six months, those who received a 50-microgram dose of the new vaccine doubled their antibodies against the Omicron variant compared to the original booster, and increased their antibody levels against the Delta variant.

Moderna CEO Stephanie Bancel said the new clinical data shows good protection against the variants.

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The booster was "generally well-tolerated" by participants who received both the 50-microgram and 100-microgram doses, with some reports of soreness at the injection site, fatigue and muscle pain, the company said.

Moderna is testing another vaccine that could be available as early as this fall. It targets the Wuhan strain and 32 mutations in the Omicron variant. The Food and Drug Administration said it will wait until June to decide whether new COVID-19 shots targeting variants are needed.


Some FDA committee members, including Dr. Paul Offit, said it is not up to the biotech companies to decide, CNBC reported.

RELATED White House COVID-19 coordinator urges adults over 60 to get second booster

"You often hear that the company now has an Omicron-specific vaccine, or vaccine they can now link with the influenza vaccine. It shouldn't come from them, it really has to come from us," he said.

RELATED FDA approves 2nd booster of Pfizer, Moderna vaccines for 50 and over

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