In an interview with CBS Face the Nation moderator Margaret Brennan that aired Sunday, Trump didn't specify what conditions would prompt the United States to take military action as National Assembly President Juan Guaido -- who has been backed by the United States -- challenges Maduro's presidency, but he hadn't ruled it out.
"Well I don't want to say that. But certainly it's something that's on the -- it's an option," Trump said when asked about the possibility.
Trump added that Maduro requested a meeting with him "a number of months ago," but declined because the United States was already "very far along in the process" of supporting Guaido, although he only formally recognize the opposition leader as Venezuela's interim president on Jan. 23.
"You have a young and energetic gentleman but you have other people within that same group that have been very very -- if you talk about democracy -- it's really democracy in action," Trump said.
He also cited "many really horrible things" that have been happening in Venezuela for his decision to turn down the meeting.
"That was the wealthiest country of all in that part of the world which is a very important part of the world. And now you look at the poverty and you look at the anguish and you look at the crime and you look at all of the things happening," Trump said. "So, I think the process is playing out -- very, very big tremendous protests."
Trump also addressed his disagreement with the U.S. intelligence community its belief that more work needs to be done to combat the Islamic State in Syria before withdrawing U.S. troops by reiterating his assertion that the terror group has largely been eradicated.
"You have the caliphate almost knocked out," Trump said. "We will be announcing in the not too distant future 100 percent of the caliphate, which is the area -- the land -- the area, 100. We're at 99 percent right now, we'll be at 100," Trump said.
The president went on to say that he doesn't "have to agree" with his intelligence chiefs and the information they provide him if it isn't consistent with his personal counsel.
"My intelligence people, if they said in fact that Iran is a wonderful kindergarten, I disagree with them 100 percent. It is a vicious country that kills many people," Trump said. "We were in many, many locations in the Middle East, in huge difficulty. Every single one of them was caused by the number one terrorist nation in the world which is Iran. So when my intelligence people tell me how wonderful Iran is --- if you don't mind, I'm going to just go by my own counsel."
Further discussing the Syria withdrawal, Trump said the 2,000 troops are slowly beginning to leave the country while combating the "final remainder of the caliphate" and they will later "be going to our base in Iraq, and ultimately, some will be coming home."
He added a small contingent of troops will also be kept in Afghanistan for "real intelligence" purposes.
"I'll leave intelligence there and if I see nests forming, I'll do something about it," Trump said.
Trump expressed if the Islamic State or al Qaeda terror groups experienced a resurgence after the troops are withdrawn he would simply send forces back.
"We have very fast airplanes, we have very good cargo planes. We can come back very quickly, and I'm not leaving. We have a base in Iraq and the base is a fantastic edifice. I mean I was there recently, and I couldn't believe the money that was spent on these massive runways. And these -- I've rarely seen anything like it. And it's there. And we'll be there," he said.
Trump also said that he requested former defense secretary, James Mattis, resign due to his displeasure with how Mattis handled Syria, Afghanistan and Iraq.
"I wasn't happy with his service. I told him, 'Give me a letter,'" Trump said. "He resigned because I asked him to resign. "He resigned because I was very nice to him.
"I gave him big budgets and he didn't do well in Afghanistan. I was not happy with the job he was doing in Afghanistan. And if you look at Syria what's happened. I went to Iraq recently, if you look at Syria, what's happened in Syria in the last few weeks, you would see that things are going down that were not going down. That things are happening that are very good. So I was not happy with him, but I wish him well."
The interview was conducted in the Blue Room of the White House on Friday before he departed for his Mar-a-Lago estate in Palm Beach Fla. On Sunday, he plans to watch at least some of the Super Bowl at party in the resort before returning to Washington.