Pelosi spoke in response to Rep. Eric Cantor, R-Va., who said some people in Washington "have actually condoned the pitting of Americans against Americans," in regards to the protests.
Pelosi is the House minority leader. Cantor is the House majority leader.
"But it's the American system. It's the democratic system. We don't all agree. We'd have a king if we were all of one mind. We don't. We have different views. Part of the democracy of our country is the expression that people give, and the Constitution guarantees that," Pelosi said in an interview on ABC's "This Week."
She criticized Cantor characterizing the rallies as "pitting Americans against Americans," saying he didn't speak up when fellow Republicans showed support of Tea Party demonstrators who were spitting on members of Congress.
"He and his colleagues were putting signs in the windows encouraging them," Pelosi said.
She said the Occupy Wall Street protests represent Americans' value in fairness.
"We all have a responsibility to grow our economy, reduce the deficit, keep us No. 1. ... Listen to Ronald Reagan, when he talked about how unfair it was for a bus driver to be paying at the same rate as a millionaire. Listen to Ronald Reagan talk about that; he speaks beautifully to the unfairness of that scenario," she said.