"I think putting out a schedule where the No. 5 in the world is playing on Court 5, fifth match on after 11 (p.m. ET) -- I think that's unacceptable, you know," the 27-year-old Wozniacki told reporters.
"And when you look on Center Court -- I understand completely the business side of things and everything -- but someone who comes back from a drug sentence -- performance enhancing drugs -- and then all of a sudden gets to play every single match on Center Court, I think that's a questionable thing to do."
Sharapova is competing in her first major since her 15-month doping suspension ended in April. The Russian followed up her first-round upset of second-seeded Simona Halep with a 6-7 (4), 6-4, 5-1 victory over Hungarian Timea Babos on Wednesday.
A former No. 1 player in the world, Wozniacki reached the U.S. Open final in 2009 and 2014. She will not be advancing that far this season after dropping a 6-2, 6-7 (5), 6-1 decision in her second-round match to unranked Russian Ekaterina Makarova on Wednesday.
"I think it doesn't set a good example, and I think someone who has fought their way back from injury and is 5 in the world deserves to play on a bigger court than Court No. 5," Wozniacki said. "Finally they moved us to Court 17, which is a really nice court actually, and we had a great atmosphere out there. But I think they should probably look into what they need to do in the future."