Murray, NASCAR driver Bubba Wallace, Seattle Seahawks safety Jamal Adams and former NFL running back Marshawn Lynch alternated controlling the NFC team to earn the victory on Sunday. The game streamed on the NFL's social media accounts.
The Pro Bowl had to be played virtually this year due to the coronavirus pandemic. Players were selected for the All-Star teams in December.
Cook scored a rushing touchdown to start the scoring for the NFC in the first quarter. The AFC responded with a passing score from Kansas City Chiefs quarterback Patrick Mahomes to Los Angeles Chargers wide receiver Keenan Allen.